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Antigenic Specificity | RNF128 (Center), 115-143 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.29 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RNF128 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128. The protein encoded by this gene is a type I transmembraneprotein that localizes to the endocytic pathway. This proteincontains a RING zinc-finger motif and has been shown to possess E3ubiquitin ligase activity. Expression of this gene in retrovirallytransduced T cell hybridoma significantly inhibitsactivation-induced IL2 and IL4 cytokine production. Inducedexpression of this gene was observed in anergic CD4(+) T cells,which suggested a role in the induction of anergic phenotype.Alternatively spliced transcript variants encoding distinctisofo |
Immunogen | n/a |
Other Names | [E3 ubiquitin-protein ligase RNF128; 632-; Gene related to anergy in lymphocytes protein; GRAIL; RING finger protein 128; RNF128] |
Gene, Accession # | [RNF128], Gene ID: 79589, NCBI: NP_078815.3, UniProt: Q8TEB7 |
Catalog # | MBS9214234 |
Price | $165, $370 |
Order / More Info | RNF128 (Center), 115-143 Antibody from MYBIOSOURCE INC. |
Product Specific References | Su, L.L., et al. J. Immunol. 183(1):438-444(2009) Lin, J.T., et al. J. Immunol. 182(10):5919-5928(2009) Lineberry, N., et al. J. Biol. Chem. 283(42):28497-28505(2008) Egawa, S., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 295 (1), G163-G169 (2008) : Kostianovsky, A.M., et al. J. Immunol. 178(10):6158-6163(2007) |