RNF128 (Center), 115-143 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRNF128 (Center), 115-143
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.29
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis RNF128 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128. The protein encoded by this gene is a type I transmembraneprotein that localizes to the endocytic pathway. This proteincontains a RING zinc-finger motif and has been shown to possess E3ubiquitin ligase activity. Expression of this gene in retrovirallytransduced T cell hybridoma significantly inhibitsactivation-induced IL2 and IL4 cytokine production. Inducedexpression of this gene was observed in anergic CD4(+) T cells,which suggested a role in the induction of anergic phenotype.Alternatively spliced transcript variants encoding distinctisofo
Immunogenn/a
Other Names[E3 ubiquitin-protein ligase RNF128; 632-; Gene related to anergy in lymphocytes protein; GRAIL; RING finger protein 128; RNF128]
Gene, Accession #[RNF128], Gene ID: 79589, NCBI: NP_078815.3, UniProt: Q8TEB7
Catalog #MBS9214234
Price$165, $370
Order / More InfoRNF128 (Center), 115-143 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSu, L.L., et al. J. Immunol. 183(1):438-444(2009) Lin, J.T., et al. J. Immunol. 182(10):5919-5928(2009) Lineberry, N., et al. J. Biol. Chem. 283(42):28497-28505(2008) Egawa, S., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 295 (1), G163-G169 (2008) : Kostianovsky, A.M., et al. J. Immunol. 178(10):6158-6163(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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