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Antigenic Specificity | FAS - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | goat, human, porcine |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against FAS. It was validated on Western BlotTarget Description: FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also show |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FAS |
Other Names | [tumor necrosis factor receptor superfamily member 6 isoform 1; Tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; Fas cell surface death receptor; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor] |
Gene, Accession # | [FAS], Gene ID: 355, NCBI: NP_000034, UniProt: P25445 |
Catalog # | MBS3214191 |
Price | $335 |
Order / More Info | FAS - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |