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Antigenic Specificity | SOCS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.7mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
Immunogen | Immunogen: Synthetic peptide of human SOCS1 Calculated Molecular Weight: 24kDa |
Other Names | [JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, SOCS-1] |
Gene, Accession # | [SOCS1], Gene ID: 8651, NCBI: NP_003736.1 |
Catalog # | MBS2519094 |
Price | $110, $150, $225 |
Order / More Info | SOCS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |