AANAT (N-term), 27-54 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AANAT (N-term), 27-54 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT. AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. |
| Immunogen | n/a |
| Other Names | [Serotonin N-acetyltransferase; Serotonin acetylase; Aralkylamine N-acetyltransferase; AA-NAT; AANAT; SNAT] |
| Gene, Accession # | [AANAT], Gene ID: 15, NCBI: NP_001079.1, UniProt: Q16613 |
| Catalog # | MBS9201448 |
| Price | $165, $370 |
| Order / More Info | AANAT (N-term), 27-54 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Mansour, H.A., et al. Bipolar Disord 11(7):701-710(2009) Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) Anderson, B.M., et al. Neurogenetics 10(3):209-216(2009) |
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MYBIOSOURCE INC.
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