Phospho-RanBP3 (Ser126/58) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-RanBP3 (Ser126/58) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-RanBP3 (Ser126/58) antibody detects endogenous levels of RanBP3. Function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.Subunit Structure: Interacts with CHC1 in a Ran-stimulated manner. Interacts with XPO1. Interacts (via i |
| Immunogen | Immunogen: A synthesized peptide derived from human RanBP3 around the phosphorylation site of Ser126/58. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed with high levels in testis and heart. |
| Other Names | [DKFZp586I1520; Ran binding protein 3; Ran-binding protein 3; RANB3_HUMAN; RanBP3] |
| Gene, Accession # | [RanBP3], Gene ID: 8498, NCBI: NP_001287794.1, UniProt: Q9H6Z4 |
| Catalog # | MBS9600722 |
| Price | $240, $280 |
| Order / More Info | Phospho-RanBP3 (Ser126/58) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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