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Antigenic Specificity | p63 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.59-0.63 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), IMM, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Tumor protein 63 isoform 6 Antibody. Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-100 on human p63 protein. Expression: Widely expressed, notably in heart, kidney, placenta, prostate, skeletal muscle, testis and thymus, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast, eye and prostate express high levels of DeltaN-type i |
Other Names | [AIS; Amplified in squamous cell carcinoma; B(p51A); B(p51B); Chronic ulcerative stomatitis protein; CUSP; DN p63 alpha 1; EEC3; Keratinocyte transcription factor; KET; LMS; MGC115972; MGC192897; NBP; OFC8; p40; p51; P51/P63; p53CP; p63; P73; p73H; p73L; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; Transformation related protein 63; Trp53rp1; Trp63; Tumor protein 63; Tumor protein p53-competing protein; Tumor protein p63 deltaN isoform delta; Tumor protein p73], [TP63; TP63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); KET; P63; P73H; P73L; TP73L; p63; CUSP; TP63; p73L] |
Gene, Accession # | [p63], Gene ID: 8626, NCBI: NP_001108454, UniProt: Q9H3D4 |
Catalog # | MBS540812 |
Price | $390 |
Order / More Info | p63 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |