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Antigenic Specificity | MLK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MAP3KL4 antibody detects endogenous levels of MAP3KL4. Description: MLK4 Activates the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Homodimer. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.Function: Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.Subunit Structure: Homodimer (By similarity). Interacts with TLR4.Post-translational Modifications: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.Similarity: Belon |
Immunogen | Immunogen: A synthesized peptide derived from human MAP3KL4 |
Other Names | [dJ862P8.3; KIAA1804; M3KL4_HUMAN; Mitogen activated protein kinase kinase kinase; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4; MLK 4; Mlk4; RP5 862P8.2] |
Gene, Accession # | [MLK4], Gene ID: 84451, NCBI: NP_115811.2, UniProt: Q5TCX8 |
Catalog # | MBS9600446 |
Price | $240, $280 |
Order / More Info | MLK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |