SHANK1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SHANK1 antibody, protein, ELISA kits.
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| Antigenic Specificity | SHANK1 |
| Clone | [S22-21] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Antibody Microarray (AM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~190-220 kDa (alternative splice variants). No cross-reactivity against Shank2 or Shank3. Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (1). Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina (2). Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction an |
| Immunogen | Immunogen: Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1 |
| Other Names | [Mouse Rat SHANK1 IgG1; SHANK1 : APC/Cy7; GKAP/SAPAP interacting protein; OTTHUMP00000174437; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHAN1_HUMAN; SHANK 1; Shank1; Shank1a; Somatostatin receptor interacting protein; Somatostatin receptor-interacting protein; SPANK 1; SPANK1; SSTR interacting protein; SSTR-interacting protein; SSTRIP; Synamon] |
| Gene, Accession # | [SHANK1], Gene ID: 78957, NCBI: NP_113939.2, UniProt: Q9WV48 |
| Catalog # | MBS8002920 |
| Price | $510 |
| Order / More Info | SHANK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sheng M., and Kim E. (2000) Journal of Cell Science. 113: 1851-1856. 2. Kim J.H., et al. (2009) Exp Mol Med. 41(4): 236-242. 3. Gong Y., et al. (2009) Brain Res. 1292: 191-198. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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