TM173 (C-term), 311-340 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TM173 (C-term), 311-340 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TM173 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TM173. Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase |
| Immunogen | n/a |
| Other Names | [Stimulator of interferon genes protein; hSTING; Endoplasmic reticulum interferon stimulator; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173; TMEM173; ERIS; MITA; STING] |
| Gene, Accession # | [TMEM173], Gene ID: 340061, NCBI: NP_938023.1, UniProt: Q86WV6 |
| Catalog # | MBS9207991 |
| Price | $165, $370 |
| Order / More Info | TM173 (C-term), 311-340 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sun, W., et al. Proc. Natl. Acad. Sci. U.S.A. 106(21):8653-8658(2009) Zhong, B., et al. Immunity 30(3):397-407(2009) Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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