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Antigenic Specificity | Human BAX (N-TERMINAL) |
Clone | [2D2] |
Host Species | Mouse |
Reactive Species | African green monkey, bovine |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human BAX antibody, clone 2D2 recognizes an epitope within the N-terminal (NT) region of human apoptosis regulator BAX, also known as Bcl-2-like protein 4. BAX is a pro-apoptotic member of the Bcl-2 family. BAX accelerates programmed cell death by binding to and antagonizing the apoptosis repressor Bcl-2 or its adenovirus homolog E1B 19k protein. It also induces the release of cytochrome C, activation of caspase-3 and thereby apoptosis. Defects in BAX are found in some cell lines from hematopoietic malignancies as T-cell acute lymphoblastic leukemia, Burkitt lymphoma, and plasmacytoma (Brimmell et al. 1998). Mouse anti Human BAX antibody, clone 2D2 has been successfully used for the immunoprecipitation of bovine BAX from thymus ( |
Immunogen | n/a |
Other Names | [apoptosis regulator BAX isoform 1; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2-associated X protein omega; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; bcl-2-like protein 4; bcl2-L-4; BCL2-associated X protein; Bcl-2-like protein 4; Bcl2-L-4], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812 |
Catalog # | MBS214489 |
Price | $300 |
Order / More Info | Human BAX (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |