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Antigenic Specificity | Human BD-2 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptid |
Immunogen | Antibody Generation: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hBD-2. Anti-hBD-2 specific antibody was purified by affinity chromatography employing immobilized hBD-2 matrix. |
Other Names | [Antigen-Affinity Purified human BD-2], [DEFB4B; DEFB4A; DEFB4P; DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1] |
Gene, Accession # | [BD-2], Gene ID: 100289462, NCBI: NP_001192195.1, UniProt: O15263 |
Catalog # | MBS691384 |
Price | $415 |
Order / More Info | Human BD-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |