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Antigenic Specificity | HLA-C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 0.66mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the pe |
Immunogen | Immunogen: Synthetic peptide of human HLA-C |
Other Names | [HLA-JY3; D6S204; HLAC; Psoriasis Susceptibility 1; HLA-C Alpha Chain; PSORS1; MHC] |
Gene, Accession # | [HLA-C], Gene ID: 3107, NCBI: NP_002108, UniProt: P10321 |
Catalog # | MBS2559811 |
Price | $110, $150, $225 |
Order / More Info | HLA-C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |