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Antigenic Specificity | Fra-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Fra-1 protein. an oncogenic transcription factor of the bZIP family, Fos subfamily. The expression of Fos proteins is rapidly and transiently induced by a variety of extracellular stimuli including growth factors, cytokines, neurotransmitters, polypeptide hormones, and stress. Fos proteins dimerize with Jun proteins (c-Jun, JunB, and JunD) to form Activator Protein-1 (AP-1), a transcription factor that binds to TRE/AP-1 elements and activates transcription. Fos and Jun proteins contain the leucine-zipper motif that mediates dimerization and an adjacent basic domain that binds to DNA. The various Fos/Jun heterodimers differ in their ability to transactivate AP-1 dependent genes. In addition to |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human Fra-1. |
Other Names | [FOSL1; FRA-1; Fos-related antigen 1] |
Gene, Accession # | [Fra-1], Gene ID: 8061, NCBI: NP_001287773.1, UniProt: P15407 |
Catalog # | MBS9404182 |
Price | $200, $255 |
Order / More Info | Fra-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |