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Antigenic Specificity | PLAU |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PLAU Antibody detects endogenous levels of total PLAU. The human urokinase-type plasminogen activator receptor (uPAR) is a 55-65 kDa, highly glycosylated, GPI-anchored cell surface receptor (the deglycosylated protein is 35 kDa) (1-3). It is a central player in the plasminogen activation pathway. uPAR binds with high affinity to a serine protease urokinase-type plasminogen activator (uPA) and converts plasminogen to its active form plasmin in a spatially restricted manner on the cell surface (4). Plasmin further carries out the activation of uPA, which is inhibited by serpins, such as plasminogen activator inhibitors (5). Therefore, uPAR plays a key role in regulating extracellular proteolysis. In addition, uPAR plays an import |
Immunogen | Immunogen: Recombinant protein of human PLAU |
Other Names | [ATF; UPA; URK; u-PA] |
Gene, Accession # | [PLAU], Gene ID: 5328, NCBI: NP_001138503.1, UniProt: P00749 |
Catalog # | MBS8516374 |
Price | $290 |
Order / More Info | PLAU Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |