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Antigenic Specificity | HDAC4 (N-term) |
Clone | [4A3-H7-C6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs a |
Immunogen | Immunogen: Purified recombinant human HDAC4 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of HDAC4 and does not cross-react with related proteins. Sequence Similarities: Belongs to the histone deacetylase family. HD type 2 subfamily |
Other Names | [EC 3.5.1.98; HA6116; HD 4; HD4; HDAC 4; HDAC A; HDAC4; HDAC4_HUMAN; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288], [HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A] |
Gene, Accession # | [HDAC4], Gene ID: 9759, NCBI: NP_006028.2, UniProt: P56524 |
Catalog # | MBS475081 |
Price | $335 |
Order / More Info | HDAC4 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |