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Antigenic Specificity | P38 MAPK(Phospho-Thr180/Tyr182) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of P38 MAPK Protein only when phosphorylated at threonine 180/tyrosine 182. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets. RP |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine 180 or tyrosine 182 (E-M-T(p)-G-Y(p)-V-A) derived from Human P38 MAPK. |
Other Names | [RK, p38, CSBP, EXIP, Mxi2] |
Gene, Accession # | [P38 MAPK], NCBI: AAR17088.1 |
Catalog # | MBS9403039 |
Price | $200, $255 |
Order / More Info | P38 MAPK(Phospho-Thr180/Tyr182) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |