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Antigenic Specificity | B2L10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of B2L10 protein. The protein encoded by BCL2L10 (BCL2 Like 10) belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by BCL2L10 contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X (L), and BAX. Overexpression of BCL2L10 has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms |
Immunogen | Immunogen: Synthesized peptide derived from part region of human B2L10 protein at amino acid sequence of 70-150 |
Other Names | [Rabbit B2L10; Bcl-2-like protein 10; Bcl2-L-10; apoptotic protein NrH; Apoptosis regulator Bcl-B] |
Gene, Accession # | [B2L10], Gene ID: 10017, NCBI: NP_065129.1, UniProt: Q9HD36 |
Catalog # | MBS9708460 |
Price | $130, $220, $325 |
Order / More Info | B2L10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |