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Antigenic Specificity | Phospho-REPS1 (Ser709) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-REPS1 (Ser709) antibody detects endogenous levels of REPS1. Function: May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.Subunit Structure: Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase (By similarity). Interacts with AMPH, ITSN1 (via SH3 domains) and SGIP1; may be involved in clathrin-mediated endocytosis.Post-translational Modifications: EGF stimulates phosphorylation on Tyr-residues. |
Immunogen | Immunogen: A synthesized peptide derived from human REPS1 around the phosphorylation site of Ser709. Subcellular Location: Membrane > Clathrin-Coated Pit. Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits. Tissue Specificity: Widely expressed with highest levels in heart and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100 |
Other Names | [RALBP1; RalBP1 associated Eps domain containing protein 1; RalBP1 interacting protein 1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; REPS1; REPS1_HUMAN] |
Gene, Accession # | [REPS1], Gene ID: 85021, NCBI: NP_001122089.1, UniProt: Q96D71 |
Catalog # | MBS9600724 |
Price | $240, $280 |
Order / More Info | Phospho-REPS1 (Ser709) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |