Phospho-REPS1 (Ser709) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-REPS1 (Ser709)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Phospho-REPS1 (Ser709) antibody detects endogenous levels of REPS1. Function: May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.Subunit Structure: Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase (By similarity). Interacts with AMPH, ITSN1 (via SH3 domains) and SGIP1; may be involved in clathrin-mediated endocytosis.Post-translational Modifications: EGF stimulates phosphorylation on Tyr-residues.
ImmunogenImmunogen: A synthesized peptide derived from human REPS1 around the phosphorylation site of Ser709. Subcellular Location: Membrane > Clathrin-Coated Pit. Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits. Tissue Specificity: Widely expressed with highest levels in heart and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100
Other Names[RALBP1; RalBP1 associated Eps domain containing protein 1; RalBP1 interacting protein 1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; REPS1; REPS1_HUMAN]
Gene, Accession #[REPS1], Gene ID: 85021, NCBI: NP_001122089.1, UniProt: Q96D71
Catalog #MBS9600724
Price$240, $280
Order / More InfoPhospho-REPS1 (Ser709) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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