MD-2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MD-2 |
| Clone | [9F1B1] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4. |
| Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2 |
| Other Names | [MD-2 (9F1B1): Lymphocyte antigen 96 precursor, ESOP-1] |
| Gene, Accession # | [MD-2], Gene ID: 23643, NCBI: NP_056179 |
| Catalog # | MBS9400073 |
| Price | $320 |
| Order / More Info | MD-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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