Edit |   |
---|---|
Antigenic Specificity | DR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DR4 Polyclonal Antibody detects endogenous levels of DR4 protein. TNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human DR4 at AA range: 370-450 |
Other Names | [Rabbit DR4; TNFRSF10A; APO2; DR4; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD antigen CD261] |
Gene, Accession # | [DR4], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220 |
Catalog # | MBS9701910 |
Price | $130, $220, $325 |
Order / More Info | DR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |