SGK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySGK1
Clone[4D12]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein A purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentrationn/a
ApplicationsImmunohistochemistry Paraffin (IHC-p)
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DescriptionProtein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, KCNA3/Kv1.3 or EAAT1. Isoform 2 exhibited a greater effect on cell plasma membrane expression of ENaC and Na(+) transport than isoform 1.
ImmunogenImmunogen: Synthetic Peptide of SGK1
Other Names[SGK1]
Gene, Accession #[SGK1], Gene ID: 6446, NCBI: NP_001137148.1, UniProt: O00141
Catalog #MBS2548977
Price$110, $150, $225
Order / More InfoSGK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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