PTPN11 (pTyr542) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPTPN11 (pTyr542)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (expected from sequence), rat (expected from sequence)
Isotypen/a
Formataffinity purified
Size0.05 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRabbit anti PTPN11 (pTyr542) antibody recognizes PTPN11 also known as tyrosine-protein phosphatase non-receptor type 11, PTP2C or SHPTP2, when phosphorylated at tyrosine 542. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPN11 contains two Src homology-2 domains which bind phospho-tyrosine domains. PTPs regulate numerous cellular functions including cell proliferation and oncogenic transformation. EphA2 has been identified as a kinase that phosphorylates PTPN11 at tyrosine 542 leading to the recruitment of Grb2 (Miura et al. 2013).
ImmunogenImmunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 542 of human PTPN11
Other Names[PTPN11 (pTyr542)], [PTPN11; PTPN11; CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3; PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2]
Gene, Accession #[PTPN11], Gene ID: 5781, NCBI: Q06124.2, UniProt: Q06124
Catalog #MBS225308
Price$375
Order / More InfoPTPN11 (pTyr542) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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