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Antigenic Specificity | PTPN11 (pTyr542) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti PTPN11 (pTyr542) antibody recognizes PTPN11 also known as tyrosine-protein phosphatase non-receptor type 11, PTP2C or SHPTP2, when phosphorylated at tyrosine 542. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPN11 contains two Src homology-2 domains which bind phospho-tyrosine domains. PTPs regulate numerous cellular functions including cell proliferation and oncogenic transformation. EphA2 has been identified as a kinase that phosphorylates PTPN11 at tyrosine 542 leading to the recruitment of Grb2 (Miura et al. 2013). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 542 of human PTPN11 |
Other Names | [PTPN11 (pTyr542)], [PTPN11; PTPN11; CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3; PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2] |
Gene, Accession # | [PTPN11], Gene ID: 5781, NCBI: Q06124.2, UniProt: Q06124 |
Catalog # | MBS225308 |
Price | $375 |
Order / More Info | PTPN11 (pTyr542) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |