KPNA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKPNA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionKaryopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind cargo and three intervening nuclear localization sequences (NLSs)
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human KPNA2.
Other Names[Karyopherin alpha nucleoprotein interactor 2, Importin alpha2, IPOA1, RAG cohort protein 1, RCH1, SRP1, QIP2]
Gene, Accession #[KPNA2], Gene ID: 3838, NCBI: NP_002257
Catalog #MBS9406319
Price$320
Order / More InfoKPNA2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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