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Antigenic Specificity | KPNA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind cargo and three intervening nuclear localization sequences (NLSs) |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human KPNA2. |
Other Names | [Karyopherin alpha nucleoprotein interactor 2, Importin alpha2, IPOA1, RAG cohort protein 1, RCH1, SRP1, QIP2] |
Gene, Accession # | [KPNA2], Gene ID: 3838, NCBI: NP_002257 |
Catalog # | MBS9406319 |
Price | $320 |
Order / More Info | KPNA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |