Edit |   |
---|---|
Antigenic Specificity | HNRNPU |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA-and RNA-binding protein involved in several cellular processes such as nuclear chromatin organization, telomere-length regulation, transcription, mRNA alternative splicing and stability, Xist-mediated transcriptional silencing and mitotic cell progression (PubMed:10490622, PubMed:18082603, PubMed:19029303, PubMed:22325991, PubMed:25986610, PubMed:28622508). Plays a role in the regulation of interphase large-scale gene-rich chromatin organization through chromatin-associated RNAs (caRNAs) in a transcription-dependent manner, and thereby maintains genomic stability (PubMed:1324173, PubMed:8174554, PubMed:28622508). Required for the localization of the long non-coding Xist RNA on the inactive chromosome X (Xi) and the subsequent initiation |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 608-825 of human HNRNPU (NP 114032.2). |
Other Names | [SAFA; HNRPU; SAF-A; U21.1; pp120; EIEE54; GRIP120; hnRNP U; HNRNPU-AS1] |
Gene, Accession # | [HNRNPU], Gene ID: 3192, NCBI: Q00839.6, UniProt: Q00839 |
Catalog # | MBS8545307 |
Price | $280 |
Order / More Info | HNRNPU Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |