CATB (Center), 198-227 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CATB (Center), 198-227 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CATB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human CATB. The protein CATB is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. |
| Immunogen | n/a |
| Other Names | [Cathepsin B; APP secretase; APPS; Cathepsin B1; Cathepsin B light chain; Cathepsin B heavy chain; CTSB; CPSB] |
| Gene, Accession # | [CTSB], Gene ID: 1508, NCBI: NP_001899.1, UniProt: P07858 |
| Catalog # | MBS9207457 |
| Price | $165, $370 |
| Order / More Info | CATB (Center), 198-227 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang,H., J. Immunol. 182 (11), 6993-7000 (2009) Duncan,J.A., J. Immunol. 182 (10), 6460-6469 (2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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