CTLA4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTLA4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.8 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total CTLA4 protein. This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human Cytotoxic T-lymphocyte protein 4
Other Names[CD; GSE; GRD4; ICOS; CD152; CTLA-4; IDDM12; CELIAC3]
Gene, Accession #[CTLA4], Gene ID: 1493, NCBI: NP_001032720.1, UniProt: P16410
Catalog #MBS9403611
Price$255
Order / More InfoCTLA4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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