Edit |   |
---|---|
Antigenic Specificity | Ret |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information. Required for the molecular mechanisms orchestration during intestine organogenesis; involved in the development of enteric nervous system and renal organogenesis during embryonic life, and promotes the formation of Peyer's patch-like structures, a major component of the gut- associated lymphoid tissue. Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an i |
Immunogen | Immunogen: A synthesized peptide derived from human Ret. Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. |
Other Names | [Proto-oncogene tyrosine-protein kinase receptor Ret; 2.7.10.1; Cadherin family member 12; Proto-oncogene c-Ret; Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; RET; CDHF12; CDHR16; PTC; RET51], [RET; RET; PTC; MTC1; HSCR1; MEN2A; MEN2B; CDHF12; CDHR16; RET-ELE1; CDHF12; CDHR16; PTC; RET51] |
Gene, Accession # | [Ret], Gene ID: 5979, NCBI: NP_065681.1, UniProt: P07949 |
Catalog # | MBS179246 |
Price | $160, $340, $340 |
Order / More Info | Ret Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |