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Antigenic Specificity | GSDMD |
Clone | [2E6C7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1beta secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. |
Immunogen | Immunogen: Fusion protein of GSDMD |
Other Names | [1810036L03Rik; DF 5L; DF5L; DFNA 5L; DFNA5L; FKSG 10; FKSG10; FLJ12150; Gasdermin D; Gasdermin domain containing 1; Gasdermin domain containing protein 1; Gasdermin domain-containing protein 1; Gasdermin-D; GasderminD; GSDMD; GSDMD; GSDMDC 1; GSDMDC1] |
Gene, Accession # | [GSDMD], Gene ID: 79792, NCBI: NP_001159709.1, UniProt: P57764 |
Catalog # | MBS2530016 |
Price | $220, $290, $435 |
Order / More Info | GSDMD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |