Mouse VEGFR-3/FLT-4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse VEGFR-3/FLT-4 |
| Clone | [7A3] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis. |
| Immunogen | Preparation: The hybridoma was generated after fusion with cells from rat immunized with purified, insect cell-derived recombinant mouse soluble FLT-4 (120 kDa) as the immunizing antigen. Rat IgG1 antibody from hybridomas was purified from cell culture supernatant by Protein G chromatography. |
| Other Names | [Mouse VEGFR-3/FLT-4 (#7A3); vascular endothelial growth factor receptor-3; Flt4; Chy; Flt-4; VEGFR3; VEGFR-3;], [Flt4; Flt4; Chy; Flt-4; VEGFR3; VEGFR-3; AI323512; Flt-4; Vegfr3; VEGFR-3; FLT-4] |
| Gene, Accession # | [VEGFR-3/FLT-4], Gene ID: 14257, NCBI: NP_032055.1, UniProt: P35917 |
| Catalog # | MBS690799 |
| Price | $365 |
| Order / More Info | Mouse VEGFR-3/FLT-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Joukov et al, (1996), EMBO J, 15: 290; Kukk et al., (1996), Development, 122: 3829 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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