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Antigenic Specificity | Human ATF2 (pSer490/pSer498) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human ATF2 antibody recognizes ATF2, also known as activating transcription factor 2, when phosphorylated at serine 490 and serine 498. The ATF2 gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. Several studies implicate abnormal activation of ATF-2 in growth and progression of mammalian skin tumors. ATF2 may mediate oncogenesis caused by mutant Ras protein and regulate maintenance of the aggressive cancer phenotype of some types of epithelial cells. ATF2 has also been shown to be phosphorylate |
Immunogen | n/a |
Other Names | [Cyclic AMP-dependent transcription factor ATF-2; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-dependent transcription factor ATF-2; activating transcription factor 2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; Histone acetyltransferase ATF2; cAMP response element-binding protein CRE-BP1], [ATF2; ATF2; HB16; CREB2; TREB7; CREB-2; CRE-BP1; CREB2; CREBP1; cAMP-dependent transcription factor ATF-2; CREB-2; cAMP-responsive element-binding protein 2] |
Gene, Accession # | [ATF2], Gene ID: 1386, NCBI: P15336.4, UniProt: P15336 |
Catalog # | MBS224883 |
Price | $470 |
Order / More Info | Human ATF2 (pSer490/pSer498) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |