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Antigenic Specificity | Human FZD5 / Frizzled 5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | gorilla, human. predicted reactivity: Gibbon, monkey, mouse, rat, bovine, dog, porcine, rabbit (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human FZD5 / Frizzled 5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ART5 (44%). FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. |
Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human FZD5 / Frizzled 5. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Mouse, Rat, Elephant, Dog, Bovine, Rabbit, Pig (94%); Marmoset (88%). |
Other Names | [FZD5 / Frizzled 5 (Cytoplasmic Domain) IHC-plus; FZD5; C2orf31; DKFZP434E2135; Frizzled family receptor 5; Fz5; Fzd-5; FzE5; Frizzled 5; Frizzled-5; Wnt receptor; Fz-5; HFZ5; Human FZD5; Frizzled 5], [FZD5; FZD5; HFZ5; C2orf31; C2orf31; Fz-5; hFz5] |
Gene, Accession # | [FZD5], Gene ID: 7855, NCBI: NP_003459.2, UniProt: Q13467 |
Catalog # | MBS244336 |
Price | $530 |
Order / More Info | Human FZD5 / Frizzled 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |