Human Caspase-8 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Caspase-8 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human Caspase-8 |
| Clone | [SB125a1] |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | IgM |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with human Caspase 81. The Caspases are a family of cysteine proteases that induce apoptosis in response to a variety of intraand extracellular stimuli. These enzymes are synthesized as inactive precursors which become cleaved at aspartate-specific sites upon induction of apoptosis. Caspase 8 (MACH/FLICE/Mch5) is a cytosolic protease that is capable of processing/activating all known caspases, indicating its presence early in the apoptotic cascade3. It mediates cell death induction by receptors of the tumor necrosis factor (TNF) and nerve growth factor (NGF) family to eliminate injured cells and maintain leukocyte homeostasis4,5. Moreover, studies have suggested it regulates Fas-induced cytotoxicity and may have a non-apoptotic role |
| Immunogen | Immunogen: Purified native human Caspase 8. Characterization: To ensure acceptable performance, each batch of product is tested by Western blotting to conform to characteristics of a standard reference reagent. |
| Other Names | [Rat Human Caspase 8], [CASP8; caspase-8] |
| Gene, Accession # | Gene ID: 395284, NCBI: NP_989923.1 |
| Catalog # | MBS670338 |
| Price | $255 |
| Order / More Info | Human Caspase-8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Krumschnabel, G. et al. (2009). Cell Death and Diff. 16: 195-207.3) Fernandes-Alnemri, T. et al. (1996). Proc. Natl. Acad. Sci. 93: 7464-69.4) Cohen, G.M. (1997). Biochem. J. 326: 1-16.5) Kennedy, N.J. et al. (1999) J. Exp. Med. 190: 1891-6.6) Kang, T.B. et al. (2004). J. Immun. 173: 2976-84.7) Zhang, X. et al. (2003) FASEB. 17:1367-69. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies