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Antigenic Specificity | FLI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FLI1 antibody detects endogenous levels of total FLI1. Description: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11; 22)(q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4; 11)(q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.Function: Sequence-specific transcriptional activator (PubMed:24100448, PubMed:26316623, PubMed:28255014). Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.Subunit Structure: Can form homodimers or heterodimers w |
Immunogen | Immunogen: A synthesized peptide derived from human FLI1 Subcellular Location: Nucleus. |
Other Names | [ERGB transcription factor; Ewing Sarcoma breakpoint region 2; EWSR 2; EWSR2; FLI 1; FLI 1 proto oncogene; Fli-1 proto-oncogene, ETS transcription factor; FLI1; FLI1 EWS fusion gene; FLI1 proto oncogene; FLI1_HUMAN; Friend leukemia integration 1 (FLI1) transcription factor; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Sarcoma breakpoint region 2 (EWSR2); SIC 1; SIC1; Transcription factor ERGB; Viral integration region FLI1; Viral integration region FLI1, mouse, homolog of] |
Gene, Accession # | [FLI1], Gene ID: 2313, NCBI: NP_001161153.1, UniProt: Q01543 |
Catalog # | MBS9608071 |
Price | $240, $280 |
Order / More Info | FLI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |