TNF-alpha (Tumor Necrosis Factor alpha) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNF-alpha (Tumor Necrosis Factor alpha) |
| Clone | [J1D9] |
| Host Species | Mouse |
| Reactive Species | human. does not react with mouse |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Inhibits Tumor Growth, Neutralizes rTNF-alpha Mediated Cytotoxicity, Protects Mice Against Toxicity of rhTNF-alpha |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody neutralizes TNF alpha biological activities. It prevents TNF alpha induced apoptosis in Jurkat cells. It also neutralizes HurTNFamediated cytotoxicity of L929 cells and inhibits tumor growth in mice. It protects mice against toxicity of HurTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25kDa protein Tumor N |
| Immunogen | Immunogen: Recombinant human TNF-alpha |
| Other Names | [APC1, Cachectin, Differentiation inducing factor (DIF), Macrophage cytotoxic factor (MCF), Necrosin, TNF alpha, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor], [TNF; TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
| Gene, Accession # | [TNF], Gene ID: 7124, NCBI: NP_000585.2, UniProt: P01375 |
| Catalog # | MBS438568 |
| Price | $190, $340, $340 |
| Order / More Info | TNF-alpha (Tumor Necrosis Factor alpha) Antibody from MYBIOSOURCE INC. |
| Product Specific References | McLaughlin PJ; Elwood NJ; Russell SM; Andrew SM; McKenzie IF. Properties of monoclonal antibodies to human tumor necrosis factor alpha (TNF alpha). Anticancer Research, 1992, 12(4):1243-6. P. Vassalli, Annu Rev Immunol 10: 411-452 (1992). M. Paparakis, et al, Cytokine and Growth Factor Reviews 7: 223-229 (1996). A. Eigler, et al, Immunology Today 18: 487-492 (1997). Kalli K R, Kaufmann S H, et al. Molecular Pharmacology 64(6): 1434-1443 (2003). R. Pijnenborg, et al, Placenta 19(4): 231-239 (1998) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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