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Antigenic Specificity | Tuberin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Tuberin Antibody detects endogenous levels of Tuberin. Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity. |
Immunogen | Immunogen: A synthesized peptide derived from human Tuberin |
Other Names | [TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin] |
Gene, Accession # | Gene ID: 7249, NCBI: NP_000539.2, UniProt: P49815 |
Catalog # | MBS4750092 |
Price | $335 |
Order / More Info | Tuberin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |