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Antigenic Specificity | AFF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of AFF4 protein. AFF4 (AF4/FMR2 Family Member 4) is a Protein Coding gene. Diseases associated with AFF4 include Chops Syndrome and Lymphoblastic Leukemia. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Gene Expression. The protein encoded by AFF4 belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving AFF4 and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human AFF4 protein at amino acid sequence of 30-110 |
Other Names | [Rabbit AFF4; AF4/FMR2 family member 4; ALL1-fused gene from chromosome 5q31 protein; Protein AF-5q31; Major CDK9 elongation factor-associated protein] |
Gene, Accession # | [AFF4], Gene ID: 27125, NCBI: Q9UHB7.1, UniProt: Q9UHB7 |
Catalog # | MBS9708324 |
Price | $130, $220, $325 |
Order / More Info | AFF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |