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Antigenic Specificity | Sheep YWHAH / 14-3-3 Eta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, chicken, human, mouse, rabbit, rat, sheep. predicted reactivity: mammal (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes 14-3-3 eta in all mammals. It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 eta is expressed principally in the brain although it is expressed at low levels in other tissues. The protein binds alpha-synuclein, forming part of Lewy bodies in Parkinson's disease and has been linked to early-onset schizophrenia. The eta isoform binds both gremlin 1, which is overexpre |
Immunogen | Immunogen Description: Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 eta. |
Other Names | [YWHAH / 14-3-3 Eta (N-Terminus) IHC-plus; YWHAH; 14-3-3 eta; 14-3-3 protein eta; Protein AS1; YWHA1; Sheep YWHAH; 14-3-3 Eta], [YWHAH; YWHAH; YWHA1; YWHA1] |
Gene, Accession # | [YWHAH], Gene ID: 7533, NCBI: NP_003396.1, UniProt: Q04917 |
Catalog # | MBS242436 |
Price | $595 |
Order / More Info | Sheep YWHAH / 14-3-3 Eta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |