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Antigenic Specificity | ATG4D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ATG4Dprotein. Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. ysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation ma |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human ATG4D. |
Other Names | [APG4 autophagy 4 homolog D; APG4-D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); ATG4D] |
Gene, Accession # | [ATG4D], Gene ID: 84971, NCBI: NP_001268433.1, UniProt: Q86TL0 |
Catalog # | MBS9404962 |
Price | $200, $255 |
Order / More Info | ATG4D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |