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Antigenic Specificity | ARHGEF11 (Center), 605-632 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11. Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein may form acomplex with G proteins and stimulate Rho-dependent signals. Asimilar protein in rat interacts with glutamate transporter EAAT4and modulates its glutamate transport activity. Expression of therat protein induces the reorganization of the actin cytoskeletonand its overexpression induces the formation of membrane rufflingand filopodia. Two alternative transcript |
Immunogen | n/a |
Other Names | [Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF; ARHGEF11; KIAA0380] |
Gene, Accession # | [ARHGEF11], Gene ID: 9826, NCBI: NP_055599.1, UniProt: O15085 |
Catalog # | MBS9206310 |
Price | $165, $370 |
Order / More Info | ARHGEF11 (Center), 605-632 Antibody from MYBIOSOURCE INC. |
Product Specific References | Akiyama, K., et al. J. Hum. Genet. (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Ying, Z., et al. Arterioscler. Thromb. Vasc. Biol. 29(10):1657-1663(2009) Banerjee, J., et al. Biochemistry 48(33):8032-8043(2009) Zheng, M., et al. BMC Struct. Biol. 9, 36 (2009) : |