Human beta 4 Spectrin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human beta 4 Spectrin |
| Clone | [S393-2] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart (1). Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier (2). |
| Immunogen | Immunogen: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin. Immunogen Species: Human |
| Other Names | [BetaIV-spectrin sigma1; Non-erythrocytic spectrin beta chain 4; Non-erythroidspectrin beta chain 3; SPTBN4; SPTBN3; Spnb4; KIAA1642; EMBL BAB83243.1; Ensembl ENSRNOP00000028393; beta 4 Spectrin : HRP; Mouse Human beta 4 Spectrin, Clone S393-2; beta 4 spectrin; beta 4 Spectrin], [SPTBN4; SPTBN4; QV; SPNB4; SPTBN3; KIAA1642; SPTBN3] |
| Gene, Accession # | [SPTBN4], Gene ID: 57731, NCBI: NP_066022.2, UniProt: Q9H254 |
| Catalog # | MBS806977 |
| Price | $425 |
| Order / More Info | Human beta 4 Spectrin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Genes and mapped phenotypes. (n.d.). Retrieved March 12, 2015, from http://www.ncbi.nlm.nih.gov/gene/57731 2. Yang Y., Lacas-Gervais S., Morest D.K., Solimena M., and Rasband M.N. (2004) J Neurosci. 24(33): 7230-7240. |
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