TLR3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR3
Clone[ABM15D5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1 kappa
Formatfluorescein (FITC) conjugate
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionTLR3 (Toll-Like Receptor-3) acts as a major receptor in virus-mediated innate immune response. This protein belongs to TLR (Toll-like receptor) family which comprises of 10-12 type I integral membrane receptor paralogs that recognize pathogen associated molecular signatures and initiate inflammatory responses. TLR3 consist of pathogen-binding ECD (Ectodomains) and cytoplasmic signaling domains, known as TIR (Toll IL-1 Receptor) domains, joined by a single transmembrane helix. TLR3 specifically senses dsRNA (Double-stranded RNA), an almost universal viral intermediate generated during most viral replications. TLR-3 activation induces multiple cellular antiviral responses, including production of IFN-alpha/beta and up-regulation of the anti-H
ImmunogenAntigen: TLR3. Immunogen Information: A partial length recombinant TLR3 protein (amino acids 25-370) was used as the immunogen for this antibody. Conjugation: FITC
Other Names[TLR3; CD283], [TLR3; TLR3; CD283; IIAE2]
Gene, Accession #[TLR3], Gene ID: 7098, NCBI: NP_003256.1, UniProt: O15455
Catalog #MBS668952
Price$145, $290
Order / More InfoTLR3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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