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Antigenic Specificity | TLR3 |
Clone | [ABM15D5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | fluorescein (FITC) conjugate |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR3 (Toll-Like Receptor-3) acts as a major receptor in virus-mediated innate immune response. This protein belongs to TLR (Toll-like receptor) family which comprises of 10-12 type I integral membrane receptor paralogs that recognize pathogen associated molecular signatures and initiate inflammatory responses. TLR3 consist of pathogen-binding ECD (Ectodomains) and cytoplasmic signaling domains, known as TIR (Toll IL-1 Receptor) domains, joined by a single transmembrane helix. TLR3 specifically senses dsRNA (Double-stranded RNA), an almost universal viral intermediate generated during most viral replications. TLR-3 activation induces multiple cellular antiviral responses, including production of IFN-alpha/beta and up-regulation of the anti-H |
Immunogen | Antigen: TLR3. Immunogen Information: A partial length recombinant TLR3 protein (amino acids 25-370) was used as the immunogen for this antibody. Conjugation: FITC |
Other Names | [TLR3; CD283], [TLR3; TLR3; CD283; IIAE2] |
Gene, Accession # | [TLR3], Gene ID: 7098, NCBI: NP_003256.1, UniProt: O15455 |
Catalog # | MBS668952 |
Price | $145, $290 |
Order / More Info | TLR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |