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Antigenic Specificity | BAX (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BAX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX. Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
Immunogen | n/a |
Other Names | [Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX; BCL2L4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_001278357.1, UniProt: Q07812 |
Catalog # | MBS9202959 |
Price | $165, $370 |
Order / More Info | BAX (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Oltvai Z.N.,et al.Cell 74:609-619(1993). Apte S.S.,et al.Genomics 26:592-594(1995). Shi B.,et al.Biochem. Biophys. Res. Commun. 254:779-785(1999). Schmitt E.,et al.Biochem. Biophys. Res. Commun. 270:868-879(2000). Cartron P.F.,et al.Hum. Mol. Genet. 11:675-687(2002). |