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Antigenic Specificity | SYPL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1. SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intr |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the carboxy terminus of human SYPL. |
Other Names | [SYPL2, Synaptophysin-like protein 2, mitsugumin 29, MG29] |
Gene, Accession # | [SYPL2], Gene ID: 284612, NCBI: NP_001035799 |
Catalog # | MBS9402526 |
Price | $320 |
Order / More Info | SYPL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |