Phospho-Smad (Ser425) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Smad (Ser425) |
| Clone | [4C5] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | 1mg/mL |
| Applications | Immunohistochemistry (IHC) Paraffin (IHC-p) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and |
| Immunogen | Immunogen: Synthetic Peptide of Phospho-Smad3 (Ser425) Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4 Conjugation: Unconjugated |
| Other Names | [Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)] |
| Gene, Accession # | Gene ID: 4088, NCBI: NP_001138574.1, UniProt: P84022 |
| Catalog # | MBS2549862 |
| Price | $110, $150, $225 |
| Order / More Info | Phospho-Smad (Ser425) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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