Edit |   |
---|---|
Antigenic Specificity | Human Kynurenine 3-monooxygenase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. |
Immunogen | Immunogen: Recombinant human Kynurenine 3-monooxygenase protein (1-260aa) |
Other Names | [Kynurenine 3-hydroxylase; KMO], [KMO; KMO; dJ317G22.1] |
Gene, Accession # | [KMO], Gene ID: 8564, NCBI: NP_003670.2, UniProt: O15229 |
Catalog # | MBS1495061 |
Price | $120, $160 |
Order / More Info | Human Kynurenine 3-monooxygenase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |