HCAR2 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HCAR2 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, guinea pig, human, mouse, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against HCAR2. It was validated on Western BlotTarget Description: HCAR2 acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The ran |
| Immunogen | n/a |
| Other Names | [hydroxycarboxylic acid receptor 2; Hydroxycarboxylic acid receptor 2; hydroxycarboxylic acid receptor 2; hydroxycarboxylic acid receptor 2; G-protein coupled receptor 109A; G-protein coupled receptor HM74A; Niacin receptor 1; Nicotinic acid receptor] |
| Gene, Accession # | [HCAR2], Gene ID: 338442, NCBI: NP_808219, UniProt: Q8TDS4 |
| Catalog # | MBS3216207 |
| Price | $335 |
| Order / More Info | HCAR2 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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