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Antigenic Specificity | ABCB1 |
Clone | [6G11C12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also fu |
Immunogen | Immunogen: Purified recombinant fragment of human ABCB1 (AA: 632-693) expressed in E Coli. |
Other Names | [CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170], [CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170] |
Gene, Accession # | [ABCB1], Gene ID: 818265, NCBI: NP_181228.1, UniProt: Q9ZR72 |
Catalog # | MBS476494 |
Price | $335 |
Order / More Info | ABCB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |