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Antigenic Specificity | TNNT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that en |
Immunogen | Immunogen: Recombinant protein of human TNNT3 Immunogen Species: Human |
Other Names | [TNTF] |
Gene, Accession # | [TNNT3], Gene ID: 7140, NCBI: NP_001036245.1, UniProt: P45378 |
Catalog # | MBS9135309 |
Price | $200, $275, $430 |
Order / More Info | TNNT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |