DVL1 (Center), 442-470 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDVL1 (Center), 442-470
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.4
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1. DVL1, the human homolog of the Drosophila dishevelled gene(dsh) encodes a cytoplasmic phosphoprotein that regulates cellproliferation, acting as a transducer molecule for developmentalprocesses, including segmentation and neuroblast specification.DVL1 is a candidate gene for neuroblastomatous transformation. TheSchwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2Ahave been mapped to the same region as DVL1. The phenotypes ofthese diseases may be consistent with defects which might beexpected from aberrant expression of a DVL gene during de
Immunogenn/a
Other Names[Segment polarity protein dishevelled homolog DVL-1; Dishevelled-1; DSH homolog 1; DVL1]
Gene, Accession #[DVL1], Gene ID: 1855, NCBI: NP_004412.2, UniProt: O14640
Catalog #MBS9215122
Price$165, $370
Order / More InfoDVL1 (Center), 442-470 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMetcalfe, C., et al. J. Cell. Sci. 123 (PT 9), 1588-1599 (2010) : Hu, T., et al. J. Biol. Chem. 285(18):13561-13568(2010) Varelas, X., et al. Dev. Cell 18(4):579-591(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : Guo, J., et al. PLoS ONE 4 (11), E7982 (2009) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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