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Antigenic Specificity | DVL1 (Center), 442-470 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1. DVL1, the human homolog of the Drosophila dishevelled gene(dsh) encodes a cytoplasmic phosphoprotein that regulates cellproliferation, acting as a transducer molecule for developmentalprocesses, including segmentation and neuroblast specification.DVL1 is a candidate gene for neuroblastomatous transformation. TheSchwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2Ahave been mapped to the same region as DVL1. The phenotypes ofthese diseases may be consistent with defects which might beexpected from aberrant expression of a DVL gene during de |
Immunogen | n/a |
Other Names | [Segment polarity protein dishevelled homolog DVL-1; Dishevelled-1; DSH homolog 1; DVL1] |
Gene, Accession # | [DVL1], Gene ID: 1855, NCBI: NP_004412.2, UniProt: O14640 |
Catalog # | MBS9215122 |
Price | $165, $370 |
Order / More Info | DVL1 (Center), 442-470 Antibody from MYBIOSOURCE INC. |
Product Specific References | Metcalfe, C., et al. J. Cell. Sci. 123 (PT 9), 1588-1599 (2010) : Hu, T., et al. J. Biol. Chem. 285(18):13561-13568(2010) Varelas, X., et al. Dev. Cell 18(4):579-591(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : Guo, J., et al. PLoS ONE 4 (11), E7982 (2009) : |