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Antigenic Specificity | Amyloid Beta 1-42 (Abeta42) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot (IB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody specifically recognizes an epitope within Abetax-42. NOTE: When administered to young Tg2576 mice with minimal Abeta deposition, this antibody reduced Abeta accumulation in the brain. Accumulation and aggregation of amyloid beta (Abeta) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Abeta (Abeta42) and aminoterminally truncated forms of Abeta (Abetax-42) are the predominant species of Abeta typically found in diffuse and senile plaques within the AD brain. The relative levels of Abeta42 appear to be the key regulators of Abeta aggregation into amyloid; thus Abeta42 has been implicated as the initiating molecule in the pathoge |
Immunogen | Antigen: Synthetic peptide corresponding to Abeta35-42. |
Other Names | n/a |
Gene, Accession # | [Abeta42] |
Catalog # | MBS190932 |
Price | $395 |
Order / More Info | Amyloid Beta 1-42 (Abeta42) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |